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How to Map reads to a reference with alternate contigs like GRCh38 - Legacy GATK Forum
Pharmaceutics | Free Full-Text | Challenges, Solutions, and Quality Metrics of Personal Genome Assembly in Advancing Precision Medicine
Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs | Nature
Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease | eLife
Predicting HLA class II antigen presentation through integrated deep learning | Nature Biotechnology
Genes | Free Full-Text | Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct mRNA Isoforms in Human Bone Marrow Cell Subpopulations
Characterizing the Major Structural Variant Alleles of the Human Genome - ScienceDirect
Challenges and opportunities associated with rare-variant pharmacogenomics: Trends in Pharmacological Sciences
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells | Nature
Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease | bioRxiv
HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles | Communications Biology
Targeted analysis of polymorphic loci from low-coverage shotgun sequence data allows accurate genotyping of HLA genes in historical human populations | Scientific Reports
Graph-guided assembly for novel HLA allele discovery | bioRxiv
Frontiers | An Integrated Genomic, Proteomic, and Immunopeptidomic Approach to Discover Treatment-Induced Neoantigens
Proteogenomic Analysis Unveils the HLA Class I-Presented Immunopeptidome in Melanoma and EGFR-Mutant Lung Adenocarcinoma - ScienceDirect
Mapping the tumour human leukocyte antigen (HLA) ligandome by mass spectrometry - Freudenmann - 2018 - Immunology - Wiley Online Library
Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells | Nature Biomedical Engineering
Predicting HLA class II antigen presentation through integrated deep learning | Nature Biotechnology
Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads | Nature Biotechnology
Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames - ScienceDirect
Cancers | Free Full-Text | NK Cell Therapy: A Rising Star in Cancer Treatment
Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer - ScienceDirect
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire | Nature